Metronidazole Dosage Chart for Dogs: Risks, Side Effects, Dosage, and More

Written by Amber LaRock
Updated: August 23, 2023
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Has your vet prescribed metronidazole for your dog? You likely have a list of questions about what this medication is and how it works, so let’s discuss everything you need to know about metronidazole for dogs below!

In this article, we discuss the details of metronidazole use in dogs, safe doses, common side effects, and more. Let’s dive in!

What Is Metronidazole?

dog penicillin

Metronidazole is most commonly prescribed to treat bacterial infections of the digestive system in dogs.

©megaflopp/Shutterstock.com

Metronidazole is a common antibiotic that is used in human and animal medicine. While it targets an array of bacterial infections in people, it is most commonly used to tackle bacteria within the digestive tract in dogs. It is one of the most commonly prescribed antibiotics in the vet setting.

Is Metronidazole Safe For Dogs?

Metronidazole is safe for use in dogs when following guidance from your veterinarian. Metronidazole can cause serious side effects when given in excess, so it’s essential to only offer your dog the dose your veterinarian prescribes. Some liquid forms of metronidazole for humans may also contain a toxic ingredient called xylitol, so it’s best to only give your dog metronidazole that comes from your vet’s office.

Why Do Dogs Take Metronidazole?

As we mentioned above, metronidazole is most commonly used to treat gastrointestinal complications in dogs. Some of the most common uses of this medication include:

  • Diarrhea due to bacterial infections
  • Intestinal parasites like giardia
  • Inflammatory bowel disease
  • Pancreatitis
  • Dental infections

Metronidazole may be prescribed alongside other antibiotics or deworming medications. For example, when treating giardia in dogs, your vet will likely prescribe metronidazole and fenbendazole.

How To Give Metronidazole To Dogs

Dog receiving a flavored pill

Metronidazole should always be given with food to prevent nausea and vomiting.

©New Africa/Shutterstock.com

Veterinarians can prescribe metronidazole to your dog in pill or liquid form. We always suggest giving your dog their metronidazole dose with a meal, as all antibiotics can be harsh on an empty stomach. If your little one is currently taking metronidazole for an upset stomach, you do not want to add to their discomfort by giving this medication without food!

Just remember that you should only give your dog metronidazole prescribed from your vet’s office. Some liquid forms of metronidazole for humans may contain xylitol, and this ingredient is highly toxic to dogs.

What Is The Dose Of Metronidazole In Dogs?

Before we discuss the standard dose of metronidazole for dogs, we should state again that you should never give your dog metronidazole without approval from your veterinarian. With that in mind, there is a common metronidazole dose that most veterinarians stick to!

The standard metronidazole dose for dogs is 5 mg per pound of body weight. It is typically given every 12 to 24 hours for 7 to 10 days, but this will vary based on the condition your dog is experiencing. For example, when prescribed to treat giardia, metronidazole is often given for 3 to 5 days. When treating general diarrhea, it may be given up to 10 days. This is why it is important to always follow your vet’s instructions for your dog’s condition.

Are There Side Effects With Metronidazole Use In Dogs?

Metronidazole is generally safe when following your vet’s guidance, but just like any other antibiotic, it can come with a few minor side effects. Some of the most common side effects include:

  • Vomiting
  • Drooling, especially right after administering the medication
  • Decreased appetite
  • Diarrhea
  • Lethargy

Most of the above side effects can be prevented by giving your dog their metronidazole with a meal. Giving any antibiotic on an empty stomach can increase the risk of GI upset.

Common Risks Of Metronidazole Use In Dogs

Pill popper for dogs

Metronidazole overdose in dogs can lead to serious health complications, so it’s important to reach out to your vet if your dog accidently got their paws on a large amount of their medication.

©JOKE_PHATRAPONG/Shutterstock.com

The main risk of metronidazole use in dogs are the consequences of an accidental overdose. Giving too much metronidazole can lead to muscle tremors, changes in heart rate, eye twitching, agitation, and even seizing. Metronidazole overdose in dogs can lead to serious health complications, so it’s important to reach out to your vet if your dog accidently got their paws on a large amount of their medication.

Metronidazole should also be kept away from any pregnant or nursing dogs, as the metronidazole can pass through the placental and mammary barrier and potentially harm the puppies. Always speak with your vet first if you think your pregnant dog needs a course of metronidazole. They will be able to offer a safe alternative.

How Do I Get Metronidazole For My Dog?

Metronidazole is a prescription medication that can only be found at your veterinarian’s office. We suggest reaching out to your veterinary team if you think your dog can benefit from the use of metronidazole!

The photo featured at the top of this post is © Alexsander Ovsyannikov/Shutterstock.com

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About the Author

Amber LaRock is a writer at A-Z Animals primarily covering topics surrounding pet health and behavior. Amber is a Licensed Veterinary Technician with 12 years of experience in the field, and she holds a degree in veterinary technology that she earned in 2015. A resident of Chiang Mai, Thailand, Amber enjoys volunteering with animal rescues, reading, and taking care of her two cats.

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