The 8 Best Ear Infection Medicines For Dogs

Written by Shannon Amber
Published: August 23, 2022
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If you’ve noticed your dog shaking its head, pawing at its ear, or that there’s some redness inside its ear, it’s most likely the start of an ear infection. There are three types of ear infections your dog may have, and it’s important to understand the differences so you can properly care for and treat your dog.

  • Otitis Externa – inflammation that affects your dog’s outer ear
  • Otitis Media – inflammation that affects your dog’s middle ear
  • Otitis interna – inflammation that affects your dog’s inner ear

Catching an ear infection early is key to preventing more severe and uncomfortable symptoms like hearing loss, loss of balance, and uncontrollable eye movements. If your dog is exhibiting any of these symptoms, it should be seen by a veterinarian right away. 

However, it’s easy to treat an ear infection and avoid a costly vet visit. Additionally, you can take simple actions such as routine cleaning and drying your dog’s ears thoroughly after a bath or swimming to reduce the chances of an ear infection. But sometimes it’s unavoidable and requires treatment, so we’ve compiled a list of the 8 best ear infection medicines for your dog for 2022. 

  1. Zymox Otic Dog Ear Infection Treatment
  2. Zymox Otic Dog Ear Infection Treatment
    • Great substitute for other products with harsh chemicals
    • Hydrocortisone provides itch relief
    • No pre-washing required
    • Once-daily application
    • Gentle formula won't sting ears
    Check Chewy Check Amazon
  3. Curaseb Dog Ear Infection Treatment
  4. Curaseb Dog Ear Infection Treatment
    • Medicated formula combats yeast, bacteria and fungus
    • Ideal for use after waterplay/swimming or bathtime
    • No stinging
    • Fights odor and discharge
    • Safe and effective for use on dogs and cats
    Check Amazon
  5. Easotic Otic Suspension for Dogs
  6. Easotic Otic Suspension for Dogs
    • Easy-prime pump
    • Easy dosing for otic application
    • Treats infections in as little as five days
    • Requires a vet to prescribe
    Check Chewy
  7. Vet's Best Ear Relief Wash for Dogs
  8. Vet's Best Ear Relief Wash for Dogs
    • Natural formula is safe and effective
    • Vet-created product
    • Free of dyes, chemicals and preservatives
    • Alcohol-free
    • Breaks up build-up and gets rid of debris
    • Non-stinging
    Check Chewy Check Amazon
  9. MISTER BEN'S Original Ear Tonic w/Aloe for Dogs
  10. MISTER BEN'S Original Ear Tonic w/Aloe for Dogs
    • Contains soothing aloe
    • Fights and prevents infections
    • Natural ingredients are safe and effective
    • Purchase includes a free e-book on how to heal ear infections
    Check Amazon
  11. NaturPet Homeopathic Medicine for Ear Infections
  12. NaturPet Homeopathic Medicine for Ear Infections
    • Homeopathic ingredients include olive oil, calendula, aloe, and vitamin E
    • Gentle formula is effective in alleviating build-up
    • Gluten- and allergen-free
    • Regulate yeast and bacteria
    • Hydrating, anti-bacterial and anti-inflammatory ingredients
    Check Chewy Check Amazon
  13. Vet's Best Ear Relief Finger Dog Wipes
  14. Vet's Best Ear Relief Finger Dog Wipes
    • Mess-free wipes are easy to use
    • Paraben-free wipes stay fresh and moist
    • Additional natural ingredients include aloe and tea tree oil
    • Gentle on ears
    • Safe for regular use
    Check Chewy Check Amazon

Best Overall: Zymox Otic Ear Solution

Zymox Otic Ear Solution was chosen as the best overall for effectiveness, price, and ingredients. The L3 Enzyme System they patented is a great substitute for the harsh chemicals often found in solutions. It includes hydrocortisone which provides relief for itchy ears, as well as an advanced formula to cut down on biofilms that can build up and cause an infection. Additionally, it’s veterinarian strength and doesn’t require pre-washing, and only requires once daily application for 1 to 2 weeks, depending on the severity of infection. We loved that it’s suitable for dogs (and cats) of all ages. With a gentle formula that won’t sting your dog’s ears, we highly recommend Zymox Otic Ear Solution to treat your dog’s ear infection.

Best Overall
Zymox Otic Dog Ear Infection Treatment
  • Great substitute for other products with harsh chemicals
  • Hydrocortisone provides itch relief
  • No pre-washing required
  • Once-daily application
  • Gentle formula won't sting ears
Check Chewy Check Amazon

Best On A Budget: Veterinary Formula Clinical Care Ear Therapy

Between paying for quality dog food, pet insurance, routine vet visits, and plenty of toys (of course), the cost of caring for your pampered pup can add up. Just like humans, medicine can be costly, but that doesn’t mean you shouldn’t be able to afford quality choices while on a budget. This is why we selected Veterinary Formula Clinical Care Ear Therapy. Their gentle formula won’t harm your dog’s sensitive ear and will treat bacterial and fungal infections while also helping to deodorize. The bottle has an easy-to-use applicator and is safe for dogs (and cats) 3 months and older. It’s alcohol-free and suitable for repeated use making it an excellent choice to treat many causes with one solution. 

Best for All Ages: Curaseb Dog & Cat Ear Infection Treatment

For its dual use with dogs and cats of all ages, we chose Curaseb Dog & Cat Ear Infection Treatment. Their ear flush solution is medicated and veterinarian strength to combat yeast, bacteria, and fungal infections. It’s ideal for regular use after bathtime or when your pet has been swimming. The gentle formula won’t sting your pet’s ear and along with treating the infection it also helps combat any smells and discharge. It’s made in a federally regulated manufacturing facility so you can trust the quality of the solution and that it’s a safe and effective choice to treat your furry best friend. 

Best for All Ages
Curaseb Dog Ear Infection Treatment
  • Medicated formula combats yeast, bacteria and fungus
  • Ideal for use after waterplay/swimming or bathtime
  • No stinging
  • Fights odor and discharge
  • Safe and effective for use on dogs and cats
Check Amazon

Best Pump Application: Easotic Otic Suspension for Dogs

Treating ear infections can be difficult as some dogs are not too keen on holding still for treatment which is why we love the Easotic Otic Suspension for Dogs. With the long cannula, it’s easy to prime and dose the solution into your dog’s ear. Additionally, most solutions will require a week or more to effectively treat the ear infection whereas this medication treats the infection in 5 days. It’s an effective antibiotic medication that does require veterinarian approval but it is worth it to cure the uncomfortable side effects of an ear infection. 

Best Pump Application
Easotic Otic Suspension for Dogs
  • Easy-prime pump
  • Easy dosing for otic application
  • Treats infections in as little as five days
  • Requires a vet to prescribe
Check Chewy

Best All-Natural Choice: Vet’s Best Ear Relief Wash for Dogs

Some pet owners highly value natural remedies to cure their ailments and want the same peace of mind regarding the products they use for their pets. Vet’s Best Ear Relief Wash for Dogs is the perfect choice for a health-conscious pet parent. This solution was formulated by Veterinarians and is free of dyes, chemicals, or preservatives. The natural alcohol-free solution breaks down build-up and expels debris. It won’t sting your dog’s ears, is safe to use regularly, and doesn’t affect topical tick or flea treatments. You can feel good knowing you’re providing your dog with a safe and natural solution to effectively remedy their ear infection, along with supporting a company that values effective planted-based solutions for pets.

Best All-Natural
Vet's Best Ear Relief Wash for Dogs
  • Natural formula is safe and effective
  • Vet-created product
  • Free of dyes, chemicals and preservatives
  • Alcohol-free
  • Breaks up build-up and gets rid of debris
  • Non-stinging
Check Chewy Check Amazon

Best Drops: MISTER BEN’S Original Ear Tonic w/Aloe for Dogs

No pet parent wants to see their pup in discomfort, and ear infections certainly impact your dog’s demeanor. We loved MISTER BEN’S Original Ear Tonic w/Aloe for Dogs for its ability to improve symptoms within a few treatments. Key natural ingredients not only help address your dog’s ear infection but will also work to prevent future infections. Organic Aloe vera, Ginkgo, and Mullein help calm both irritation and inflammation and have excellent healing properties. Additionally, Marshmallow Root and Oregon Grape root aid in alleviating skin conditions. Besides being safe for all dog breeds NaturPet provides a free e-book on healing ear infections and makes a donation to Last Chance Animal Rescue for every bottle sold. 

Best Drops
MISTER BEN'S Original Ear Tonic w/Aloe for Dogs
  • Contains soothing aloe
  • Fights and prevents infections
  • Natural ingredients are safe and effective
  • Purchase includes a free e-book on how to heal ear infections
Check Amazon

Best Homeopathic: NaturPet Ear Drops

For sensitive ears, a natural approach is a safe way to provide relief which is why we recommend NaturPet Ear Drops Homeopathic Medicine for Ear Infections for Dogs. With natural ingredients including Olive Oil, Calendula, Aloe Vera, Vitamin E, Basil, and Bergamot Oil it’s developed to be gentle enough for even the most delicate pup. It’s veterinarian recommended and is gluten and allergen-free. These natural ingredients combined effectively alleviate build-up while also regulating yeast & bacteria. Olive oil help relieve and hydrate itchy ears, Canelndula provides strong antimicrobial and antifungal properties, and Bergamot Oil has antibacterial and anti-inflammatory capacities. Formulated with high-quality ingredients you can have peace of mind with even the most sensitive of pups and wholistically heal your furry best friend. 

Best Homeopathic
NaturPet Homeopathic Medicine for Ear Infections
  • Homeopathic ingredients include olive oil, calendula, aloe, and vitamin E
  • Gentle formula is effective in alleviating build-up
  • Gluten- and allergen-free
  • Regulate yeast and bacteria
  • Hydrating, anti-bacterial and anti-inflammatory ingredients
Check Chewy Check Amazon

Best Ear Wipes: VetWELL Dog Ear Wipes

Drops, washes, and solutions can be somewhat messy depending on how much your dog may wiggle around when trying to apply, which is why VetWELL Dog Ear Wipes were a great alternative. Conveniently packaged to retain moisture and freshness, these Paraben-free wipes containing Aloe Vera, Witch Hazel, and Tea Tree Oil were just as safe and effective at deodorizing, clearing build-up, and soothing itchy ears as traditional solutions. Their single-use designs fit over your finger so you can easily and gently wipe the infected ear and dispose of the wipe afterward. Additionally, they’re safe to use regularly, which is why VetWELL Dog Ear Wipes are a great addition to your pet care products.

Best Ear Wipes
Vet's Best Ear Relief Finger Dog Wipes
  • Mess-free wipes are easy to use
  • Paraben-free wipes stay fresh and moist
  • Additional natural ingredients include aloe and tea tree oil
  • Gentle on ears
  • Safe for regular use
Check Chewy Check Amazon

Choosing the Best Medicines to Treat Ear Infections: What to Look For

While there are many different applications on the market, you know your dog best and how well they will tolerate treatment. Gauging your dog’s comfort and sensitivities to medication will help narrow down the best option. We’ve mentioned a few considerations below to help make your decision easier for choosing the best medicine to treat your dog’s ear infection. 

Let’s look at the following in more detail:

Ingredients – 

Some treatments will contain harsh chemicals and depending on your dog’s sensitivities or how much they’ve been scratching at their ear, these may exacerbate the issue. A natural method is always a smart choice when first treating an ear infection as ingredients like Olive Oil and Aloe Vera, which are often found in wholistic solutions, will not harm or agitate an inflamed ear. Instead, they will soothe and help moisturize your dog’s ear which will reduce their scratching and cause more damage. If you find a natural approach isn’t fully alleviating your dog’s symptoms, you can look for medicated treatments which can include Hydrocortisone to address the itch, and Ketoconazole, which is an antifungal and helps combat infection. Once you understand the ingredients you can effectively select the best ear infection treatment for your dog. 

Application

To cure an ear infection you’ll have choices like washes, solutions, drops, and wipes. While they sound similar they have their differences which can impact the experience and effectiveness of healing your dog. Drops and wipes are often gentle and contain natural ingredients making them best for more sensitive ears, while washes and solutions will require massaging the product into your dog’s ear for a deeper cleanse and are often medicated or may require veterinarian approval. Understanding the various applications will help you find the best and safest choice for your pup.

The Different Types of Medicines for Ear Infections: Pros and Cons Compared

We’ve expanded on the different types of medicines to cure your dog’s ear infection so you can confidently choose the best option for your pup. If the first option doesn’t solve your dog’s ear infection you can review the other applications below to find the next viable treatment. 

  • Drops – Often made of high-quality, natural ingredients are applied with a dropper directly into your dog’s ear daily for up to two weeks and can be used regularly to keep your dog’s ears free of wax buildup and debris. 
  • Solution – Usually medicated and requires you to fill the solution in your dog’s ear, gently massage, and remove any excess solution once finished. Treatment usually lasts for one to two weeks. 
  • Wash – Can be mediated or natural and requires you to fill the wash in your dog’s ear, gently massage for 30 seconds or more, and wipe any remaining solution and debris. Treatment usually lasts for one to two weeks and can be made a part of your weekly routine to help prevent future infections.  
  • Wipes – Often made with simple, natural ingredients to gently and effectively clean your dog’s ear. Can be round, shaped to fit around your finger, or a square wipe. Pre-moistened and intended for single use without any required excess clean-up afterward. Safe to use once or twice weekly to help keep your dog’s ears clean.

Let’s look at the pros and cons of each type:

Drops

PROSCONS
Easy applicationTargeted application
High-qualityLess product for the price
Natural ingredientsMore expensive

Solution 

PROSCONS
Often medicated Requires massaging product in your dog’s ear
Natural options availableRequires clean-up of excess product
More product for the priceCan be more expensive 

Wash 

PROSCONS
Often medicated Requires massaging product in your dog’s ear
Natural options availableRequires clean-up of excess product
More product for the priceCan be messy 

Wipes 

PROSCONS
DisposableSingle-use
Pre-moistened and gentleMore costly
No clean-up requiredRequires frequent application

Verified Review: User Experience

Many pup owners raved about how effective the best overall choice, Zymox Otic Ear Solution, was at quickly curing their dog’s ear infection. One dog parent said “Our Puppy has floppy ears, very prone to infections. We treated them a few times with prescriptions from the vet. I found this product and did a seven-day course with excellent results.”

Owners were able to see results quickly, with another saying “I started with the 7-day dose, but decided to continue to 14 days to be certain the infection cleared up. Within the 2nd day, all the gunk in his ears was coming out & the smell of infection was gone. I honestly say a difference within days”.

Quality ingredients can make all the difference when treating an ear infection and for that reason, we loved Vet’s Best Ear Relief Wash for Dogs. With only 7 powerful, natural ingredients you know exactly what’s in their product and why those ingredients were chosen by veterinarians to treat ear infections. 

After an owner noticed their dog shaking their head they commented “I started cleaning his ears with this solution every morning before leaving for work. Within 2 days his ears were totally clear and no more itching/shaking. We now do a cleaning a few times a week and haven’t had any issues since. HIGHLY recommend!”. While some owners enjoyed the clove smell, others mentioned it was strong, but inevitability didn’t mind as they saw such great results using Vet’s Best Ear Relief Wash for Dogs.

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About the Author

Shannon's experience as a pet parent shapes her writing and empowers her to produce informative and engaging content. She has a wonderful poodle-terrier mix named Nelson, and together, they enjoy long walks, outdoor adventures, and playing with his many toys.

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