These Are the Best Probiotics for Dogs in 2022 (They Actually Work)

Written by Joan W.
Updated: October 24, 2022
© iStock.com/EmilyOnTime

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Probiotics are friendly bacteria. Your dog has billions of them in her intestines and stomach to aid digestion, make the immune system stronger, help fight infections, and manufacture vitamins and nutrients. This is called the microbiome, and a healthy microbiome keeps your dog energetic, healthy, and happy.

Signs of an unhealthy microbiome include symptoms such as:

  • Allergies
  • Diarrhea
  • Obesity
  • Flatulence (Gas)
  • Loose stools
  • Lethargy
  • Bloating
  • Upset stomach
  • Bad breath

Your dog’s gut health impacts overall health, and the best dog probiotics can help restore a positive balance in your dog’s digestive system. However, it’s not as simple as using any probiotic product because these powerful little microorganisms have to take up residency, thrive, and divide in order to actually impact your dog’s well-being. Some products will pass right through without benefitting your pet.

Antibiotics are known to kill some of the good gut bacteria while it eliminates the bad bacteria causing infections. Even if your pet has no obvious digestive troubles, giving them the best dog probiotics after a round of antibiotics helps restore a healthy balance.

We updated our 2022 reviews to include high-quality probiotics for dogs that are most likely to stick around and benefit your pet.

  1. Nature's Farmacy Dogzymes Probiotic Max Dog Supplement
  2. Nature's Farmacy Dogzymes Probiotic Max Dog Supplement
    • Microencapsulated supplement protects the live probiotic organisms from stomach acid
    • Great taste makes dogs happy
    • Adds probiotics as well as enzymes and prebiotics to aid digestion
    • Available in treat and powder form
    • Made in the U.S.
    Check Chewy Check Amazon
  3. PointPet Digestive Health & Probiotics Dog Supplement
  4. PointPet Digestive Health & Probiotics Dog Supplement
    • Affordable pricepoint at $25 for 120 chews
    • High bacteria concentrations
    • May help reduce allergies and itching
    • Can help improve skin issues
    • Can help control diarrhea and constipation
    • Approved for daily use
    Check Chewy Check Amazon
  5. PetHonesty Digestive Probiotics Duck Flavored Soft Chews
  6. PetHonesty Digestive Probiotics Duck Flavored Soft Chews
    • Soft chew features an enjoyable duck flavor
    • Formula includes probiotics, enzymes and pumpkin to aid digestion
    • Made in the USA
    • Free of GMOs, wheat, corn and soy
    • Vet-recommended supplement
    Check Chewy Check Amazon
  7. NWC Naturals Total-Biotics Probiotic Dog & Cat Powder Supplement
  8. NWC Naturals Total-Biotics Probiotic Dog & Cat Powder Supplement
    • Contains 14 live and stable probiotic strains
    • Also contains prebiotics
    • Probiotics absorb easily
    • GMO-free
    • Made in the USA
    Check Chewy Check Amazon
  9. Tomlyn Pre & Probiotic Powder Digestive Supplement
  10. Tomlyn Pre & Probiotic Powder Digestive Supplement
    • Packaging makes for easy transport
    • Digestive powder contains beneficial microorganisms
    • Flavorless powder makes it easy to mask in your dog's favorite food
    Check Chewy Check Amazon
  11. Wholistic Pet Organics Digest-All Plus Dog Supplement
  12. Wholistic Pet Organics Digest-All Plus Dog Supplement
    • Tropical fruits help break down food and aid digestion
    • Formula includes pineapple and papaya enzymes
    • This particular formula is beneficial for dogs with gas
    • Made in the USA
    • Free from GMOs, artificial ingredients and fillers
    Check Chewy Check Amazon
  13. Zesty Paws Ancient Elements Probiotic Bites
  14. Zesty Paws Ancient Elements Probiotic Bites
    • Six probiotic bacteria strains
    • Bison-flavored chew is appealing to dogs
    • Pineapple and papaya enzymes
    Check Chewy Check Amazon

1. Best Overall: Nature’s Farmacy Dogzymes Probiotic Max Dog Supplement

In our review, the overall best probiotics for dogs is Nature’s Farmacy Dogzymes Probiotic Max Dog Supplement because it is microencapsulated to protect the live organisms from the acid in your dog’s stomach so it has better viability to give your pet the results you want. Plus it tastes great.

Nature’s Farmacy Dogzymes includes the good bacteria you look for in a probiotic, plus it adds enzymes and prebiotics to further aid your pet’s digestion. Enzymes are the active ingredients in live foods that help your dog’s cells absorb nutrients and perform important chemical reactions. Prebiotics are the fibers that feed the good bacteria (probiotics), so they can survive and thrive inside your dog’s digestive tract and do their job.

There are two basic types of best dog probiotics, treats and powders. Nature’s Farmacy gives you a powder you can mix into any liquid or your pet’s food. It’s also made in the USA.

Best Overall
Nature's Farmacy Dogzymes Probiotic Max Dog Supplement
  • Microencapsulated supplement protects the live probiotic organisms from stomach acid
  • Great taste makes dogs happy
  • Adds probiotics as well as enzymes and prebiotics to aid digestion
  • Available in treat and powder form
  • Made in the U.S.
Check Chewy Check Amazon

2. Best Probiotic Chew: PetHonesty Digestive Probiotics Duck Flavored Soft Chews

If your dog prefers a soft chew over a powder, PetHonesty produces a flavored soft chew. These tasty treats include probiotics, enzymes, and pumpkin, which are good for your dog’s digestion and act as a prebiotic to feed the healthy bacteria in your dog’s intestines.

Made in the USA with natural duck flavor, These chews are free of GMOs, wheat, corn, soy, or chemical preservatives. Keep things running smoothly for your dog with vet-recommended supplement treats.

Best Probiotic Chew
PetHonesty Digestive Probiotics Duck Flavored Soft Chews
  • Soft chew features an enjoyable duck flavor
  • Formula includes probiotics, enzymes and pumpkin to aid digestion
  • Made in the USA
  • Free of GMOs, wheat, corn and soy
  • Vet-recommended supplement
Check Chewy Check Amazon

3. Best Value: PointPet Digestive Health & Probiotics Duck Flavored Dog Supplement

Get 120 chews for just under $25 when you purchase PointPet’s Digestive Health treat supplements. They boast a high concentration of bacteria and use a no-heat preparation to keep the probiotics and prebiotics viable.

Like other quality probiotic supplements, these treats may help reduce allergies, improve skin issues, relieve itching, or stop diarrhea and constipation. They can be used daily to support health or after a round of antibiotics to restore good bacteria in your dog’s digestive system.

Best Value
PointPet Digestive Health & Probiotics Dog Supplement
  • Affordable pricepoint at $25 for 120 chews
  • High bacteria concentrations
  • May help reduce allergies and itching
  • Can help improve skin issues
  • Can help control diarrhea and constipation
  • Approved for daily use
Check Chewy Check Amazon

4. Best Variety of Strains in a Powder: NWC Naturals Total-Biotics Probiotic Dog & Cat Powder Supplement

Probiotics is a general term that encompasses many different types of helpful digestive microorganisms and bacteria. Some products contain a few different types or strains. NWC Naturals boasts 14 live and stable probiotic strains. They also include prebiotics in each scoop of their powder.

NWC also makes extra effort to ensure their probiotics are easy to absorb by combining them with live enzymes to help activation. This supplement is made in the USA and GMO-free.

Best Variety of Strains in a Powder
NWC Naturals Total-Biotics Probiotic Dog & Cat Powder Supplement
  • Contains 14 live and stable probiotic strains
  • Also contains prebiotics
  • Probiotics absorb easily
  • GMO-free
  • Made in the USA
Check Chewy Check Amazon

5. Best Powder for Travel: Tomlyn Pre & Probiotic Powder Digestive Supplement for Dogs

A container of powder is not easy to take on trips, and if your dog doesn’t like the probiotic treats, it can complicate keeping them healthy when you’re not at home.

Tomlyn prebiotic and probiotic powder comes in 30 individual packets for easy transport and use. They cultivate the beneficial microorganisms in their digestive powder by directly feeding special microbial cultures that match what you would find in the intestines of a healthy dog.

The powder is flavorless. so you can add it to your dog’s favorite foods, even if they are picky.

Best Powder for Travel
Tomlyn Pre & Probiotic Powder Digestive Supplement
  • Packaging makes for easy transport
  • Digestive powder contains beneficial microorganisms
  • Flavorless powder makes it easy to mask in your dog's favorite food
Check Chewy Check Amazon

6. Best for Dogs With Gas: Wholistic Pet Organics Digest-All Plus Dog & Cat Supplement

The enzymes from pineapples and papaya are commonly used in human digestive enzyme supplements because they work. These natural, tropical fruits have the ability to help a digestive system break down food, and it works for dogs too!

Wholistic Pet Organics combines a potent probiotic formula with pineapple and papaya enzymes. The enzymes help your dog better absorb nutrients and improve his digestion. This may be particularly helpful for dogs with flatulence because the enzymes will help break down the food that is causing the stink bombs.

This supplement is made in the USA and is free from fillers, synthetic ingredients, GMOs, or artificial flavorings. It is made into a powder that you can add to your dog’s food.

Best for Dogs With Gas
Wholistic Pet Organics Digest-All Plus Dog Supplement
  • Tropical fruits help break down food and aid digestion
  • Formula includes pineapple and papaya enzymes
  • This particular formula is beneficial for dogs with gas
  • Made in the USA
  • Free from GMOs, artificial ingredients and fillers
Check Chewy Check Amazon

7. Best Variety of Strains in a Chew: Zesty Paws Ancient Elements Probiotic Bites Bison Flavored Soft Chews Digestive Supplement for Dogs

Zesty Paws puts six strains of probiotic bacteria into a tasty bison-flavored soft chew. A healthy treat for your dog! The ancient grain base adds prebiotics to feed the beneficial bacteria once your dog eats them.

This supplement includes the digestive enzymes from pineapple and papaya, which are bromelain and papain. These enzymes add to the digestive benefits of this chew and can reduce your dog’s gas if it’s a problem.

Best Variety of Strains in a Chew
Zesty Paws Ancient Elements Probiotic Bites
  • Six probiotic bacteria strains
  • Bison-flavored chew is appealing to dogs
  • Pineapple and papaya enzymes
Check Chewy Check Amazon

Choosing the Best: What to Look For

When choosing the best probiotics for your dog, there are three factors you want to consider. They are the CFU, the variety of strains, and other beneficial ingredients.

CFU (Colony Forming Units)

The number of CFUs on your dog’s probiotic package tells you the number of viable microorganisms in a probiotic supplement at the time of production. Depending on how they are produced, transported, and stored, that number may be less by the time you feed it to your dog. Also, not all of the microorganisms and bacteria in the supplement will actually take residence in your dog’s stomach and intestines – which is what they need to do to deliver the health benefits. For these reasons, more CFUs are better.

Variety of Microorganisms

A healthy dog will not just have one kind of active probiotic bacteria in their gut. One study found at least 17 active strains. If your probiotic supplement just has one or two types of probiotic bacteria, that can still benefit your dog. However, you’ll want to change the brand you frequently buy to introduce a variety of probiotic strains. If you can get a product with multiple strains, you are doing a better job of replenishing your dog’s healthy microbiome.

Other Beneficial Ingredients

Stomach acid is powerful and can destroy probiotics before they ever get a chance to benefit your pet. Some products aren’t viable enough and go out with the food your dog ate yesterday. When a probiotic product adds things like prebiotics to feed the new microorganisms and enzymes to aid digestion, you are improving the odds of seeing the benefits you want from the supplement.

The Different Types of Probiotics for Dogs: Pros and Cons Compared

There are two main types of probiotics for dogs. You can choose between probiotic treats and powders.

Here are some pros and cons of each type.

Soft Chews or Treats

PROSCONS
Replaces other treats with a healthy supplementMay include unnecessary ingredients to form the soft chew
Easy to store
Easy to serve

Powders

PROSCONS
Can mix into your dog’s foodMay be hard to use with kibble depending on your dog and how much they like the powder
Simple, focused supplement formula
Very low calorie

Verified Review: User Experience

Pet owners are enthusiastic about how Nature’s Farmacy Dogzymes Probiotic Max Dog Supplement helped their dogs. Different users say that their dog has stopped getting up in the middle of the night to go number two, started having firmer stools, stopped having diarrhea, or stopped vomiting. 

Users say PetHonesty Digestive Probiotics Duck Flavored Soft Chews worked great for their dogs. Even a picky dog who was having eye goobers and constant scratching and licking enjoyed the treats and stopped scratching and licking. His eyes even started to clear. Owners report their dog’s loose stools improved, their gas calmed down, and they saw their pet regain energy and vitality.

One owner who used PointPet Digestive Health and Probiotics Duck Flavored Dog Supplement said her dog had the worst smelling burps and these chews took them away! Owners report their dogs’ bowel movements improved, their stools got more sold, and stinky gas went down.

Reviewers report their dogs saw benefits with NWC Naturals Total-Biotics Probiotic Dog Supplement. Digestion improved, environmental allergies went down, stool firmed up, farts stopped, and stinky breath got better.

Pet owners say that Tomlyn Pre & Probiotic Powder Digestive Supplement for Dogs is an affordable option for quality probiotic powder. A chihuahua with severe digestive problems was able to regain weight and his energy with this supplement. Reviews say they saw diarrhea clear up, giardia clear up, paw licking stop, and helped with environmental allergies.

One owner whose mini Dachshund had uncontrollable diarrhea and was losing weight no matter how much she ate used Wholistic Pet Organics Digest-All Plus Dog Supplement, and her dog got better! Reviewers saw their dogs improve from allergies, have firmer stools, improve their temperament, and recover from parasite infestations.

Reviewers say Zesty Paws Ancient Elements Probiotic Bites Bison Flavored Soft Chews Digestive Supplement for Dogs helped their dog have less gas, better bowel movements, less itching from allergies, firmer poops, and reduced bloating. One user said he’d tried four other brands, but Zesty Paws works!

About the Author

Joan Weisman is an experienced freelance marketing strategist and copywriter who helps small businesses expand their audience and stay top of mind with customers. She loves animals and dotes on her cat and dog.

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