The 5 Best Onguard Products on Chewy Today

Written by Angie Menjivar
Published: January 19, 2023
© FamVeld/Shutterstock.com

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You want your pets to live full lives and that means letting your dogs run around in dog parks, enjoy tons of fun during walks and hikes, and have some play dates with their other furry buddies. You might have an indoor/outdoor cat that you let roam the neighborhood and make friends with other cats and other humans.

They get to live a fulfilled life but sometimes that means you have to take some extra precautions. In any one of these situations, your pet can come into contact with another flea-infested animal or ticks may adhere to their skin when they’re out enjoying nature. You might even be the one to bring these tiny pests into your home. Fleas can jump great distances and ticks can be hard to spot.

Onguard Flea & Tick Treatments

The good news is you have support. Onguard has developed a line of flea and tick spot treatments for both cats and dogs. So long as you have a cat or kitten that’s over 1.5 pounds, you can start using these doses. They come in a couple of different packs for either three months, six months, or a full year. Onguard also developed a flea and tick treatment for dogs. These use the same active ingredients, but they’re formulated for different animals.

For dogs, there is a huge variation in weight so make sure that you pick up the correct option. There is an option for small dogs, medium-sized dogs, large dogs, and extra-large dogs. Each of the doses is based on weight so pay special attention to the product before you purchase it. We explain a little bit about each treatment below and share some feedback from customers who have used this brand and enjoyed it with great success.

Top Picks: The Best Onguard Products on Chewy Today

  1. Onguard Plus Flea & Tick Spot Treatment for Cats, over 1.5 lbs
    • Flea and tick spot treatment for cats.
    • Kills all life stages of fleas and ticks on cats.
    • Available in boxes containing three, six, or 12 monthly doses.
    • Only for cats 8 weeks old and up, and between 1.5 and 22 pounds.
    Check Chewy
  2. Onguard Plus Flea & Tick Spot Treatment for Dogs, 5-22 lbs
    • Flea and tick spot treatment for dogs.
    • Kills all life stages of fleas and ticks on dogs.
    • Available in boxes containing three, six, or 12 monthly doses.
    • For dogs who are at least 8 weeks old and weigh between five and 22 pounds.
    Check Chewy
  3. Onguard Plus Flea & Tick Spot Treatment for Dogs, 23-44 lbs
    • Flea and tick spot treatment for dogs.
    • Kills all life stages of fleas and ticks on dogs.
    • Available in boxes containing three, six, or 12 monthly doses.
    • For dogs who are at least 8 weeks old and weigh between 23 and 44 pounds.
    Check Chewy
  4. Onguard Plus Flea & Tick Spot Treatment for Dogs, 45-88 lbs
    • Flea and tick spot treatment for dogs.
    • Kills all life stages of fleas and ticks on dogs.
    • Available in boxes containing three, six, or 12 monthly doses.
    • For dogs who are at least 8 weeks old and weigh between 45 and 88 pounds.
    Check Chewy
  5. Onguard Plus Flea & Tick Spot Treatment for Dogs, 89-132 lbs
    • Flea and tick spot treatment for dogs.
    • Kills all life stages of fleas and ticks on dogs.
    • Available in boxes containing three, six, or 12 monthly doses.
    • For dogs who are at least 8 weeks old and weigh between 89 and 132 pounds.
    Check Chewy

#1 Best Overall: Onguard Plus Flea & Tick Spot Treatment for Cats

Best
Onguard Plus Flea & Tick Spot Treatment for Cats, over 1.5 lbs
  • Flea and tick spot treatment for cats.
  • Kills all life stages of fleas and ticks on cats.
  • Available in boxes containing three, six, or 12 monthly doses.
  • Only for cats 8 weeks old and up, and between 1.5 and 22 pounds.
Check Chewy

The best overall Onguard product is Onguard Plus Flea & Tick Spot Treatment for Cats. This product is available in a three-month supply, a six-month supply, and a 12-month supply. It’s designed to kill fleas, flea eggs and larvae, and any chewing lice. It’s for cats and kittens that weigh over 1.5 pounds. It also kills ticks, including the ones that transmit Lyme disease.

It’s a fast-acting formula that’s also long-lasting and waterproof, which is especially important for cats you let roam outside. It’s designed to be an easy one-step application process. It incorporates two active ingredients that help stop infestations and that help to prevent any new ones. The first is fipronil which kills adult fleas, chewing lice, and ticks. The second ingredient is S-methoprene which is the one that works to prevent any future re-infestations.

Customers rate this product three out of five stars. One customer shared that her cats had an awful infestation. She keeps her cats on this product every month because it broke the flea cycle. However, she does say that you can’t just put this medication on your cat and expect that everything will work out perfectly. She reminds you that flea eggs can live in your carpets, your couches, and even in your bedding.

It’s really important that you do a full clean not just for your cats but also for the environment they live in to avoid any re-infestations. Another customer shared that she had previously been using this brand religiously but decided to try and get something a little bit more budget-friendly. She admits it was a bad decision and she quickly reverted back to this brand. She lets her cat go out freely and when she’s using Onguard, she never finds fleas on him.

Pros and Cons of Onguard Plus Flea & Tick Spot Treatment for Cats

PROSCONS
One-step application processSome cats may experience side effects with this treatment
Waterproof 
Long-lasting 

2. Best for Small Dogs: Onguard Plus Flea & Tick Spot Treatment for Dogs, 5-22 Pounds

Best for Small Dogs
Onguard Plus Flea & Tick Spot Treatment for Dogs, 5-22 lbs
  • Flea and tick spot treatment for dogs.
  • Kills all life stages of fleas and ticks on dogs.
  • Available in boxes containing three, six, or 12 monthly doses.
  • For dogs who are at least 8 weeks old and weigh between five and 22 pounds.
Check Chewy

This Onguard flea and tick spot treatment works just like the cat treatment except it’s for dogs that weigh between five and 22 pounds. It helps control the infestations of both chewing lice and sarcoptic mange mites. It also helps to break the flea life cycle and it kills tick larvae, nymphs, and adults. If your dog gets wet in the rain or plays in the water, this protection still lasts. It’s waterproof and the applicator is redesigned, which makes it easier for you to apply. So long as you use it as directed, it’s effective against fleas that cause allergy dermatitis. It’s also effective against American dog ticks, brown dog ticks, deer ticks, and Lone Star ticks.

Customers rate this product 3.4 out of five stars. One customer shared that he has two dogs he’s used this on for a whole year. He was a little bit skeptical just because it was so much more affordable than a brand he was previously using but he has no complaints. He is happy he switched over since he’s on a fixed income and he would recommend that anyone in a similar situation give this a try. Just because it’s more affordable doesn’t mean that it is less effective. Another customer shared that she loves the easy application. Previously, there would be way too much product that would just get messy. She’s really happy that they figured out how to correct that issue because a little goes a long way.

Pros and Cons of Onguard Plus Flea & Tick Spot Treatment for Dogs, 5-22 Pounds

PROSCONS
Redesigned applicatorAlthough waterproof, pups should be kept from water for 24 hours after application
Pre-filled for small dogs 
Waterproof 

3. Best for Medium-Sized Dogs: Onguard Plus Flea & Tick Spot Treatment for Dogs, 23-44 Pounds

Best for Medium-Sized Dogs
Onguard Plus Flea & Tick Spot Treatment for Dogs, 23-44 lbs
  • Flea and tick spot treatment for dogs.
  • Kills all life stages of fleas and ticks on dogs.
  • Available in boxes containing three, six, or 12 monthly doses.
  • For dogs who are at least 8 weeks old and weigh between 23 and 44 pounds.
Check Chewy

Remember that Onguard flea and tick treatment is dosed specifically based on your dog’s size. This one is for pups that weigh between 23 and 44 pounds. It’s available in three doses which is a three-month supply, six doses which is a six-month supply, and 12 doses which is a 12-month supply. Like the treatment for cats and smaller dogs, it contains the same two active ingredients: fipronil and S-methoprene. Customers rate this product 3.6 out of five stars. One dog mom shared that it works perfectly. She gave her dog a nice flea bath before and then she went ahead and applied this. She offers a suggestion to other pet parents to make sure that they are first clean before they apply this treatment.

Pros and Cons of Onguard Plus Flea & Tick Spot Treatment for Dogs, 23-44 Pounds

PROSCONS
Available in different supplies, up to a full yearThis is not a treatment designed to repel mosquitoes
Waterproof and long-lasting 
Controls infestations and prevents re-infestations 

4. Best for Large Dogs: Onguard Plus Flea & Tick Spot Treatment for Dogs, 45-88 lbs

Best for Large Dogs
Onguard Plus Flea & Tick Spot Treatment for Dogs, 45-88 lbs
  • Flea and tick spot treatment for dogs.
  • Kills all life stages of fleas and ticks on dogs.
  • Available in boxes containing three, six, or 12 monthly doses.
  • For dogs who are at least 8 weeks old and weigh between 45 and 88 pounds.
Check Chewy

If you have a bigger dog, make sure you pick up this version that’s made for dogs that way between 45 and 88 pounds. Customers rate it 3.1 out of five stars. One customer says she’s used different, more expensive brands and this one works just as well. Another customer went the opposite route and tried some cheaper brands, but they just didn’t work as well as Onguard. One dog mom says she’s been using this for years. She watches as the ticks just fall off. The treatment doesn’t leave any skin irritation. She’s very happy and recommends it.

Pros and Cons of Onguard Plus Flea & Tick Spot Treatment for Dogs, 45-88 Pounds

PROSCONS
Kills existing fleas and remains effective for thirty daysOne customer says it leaves a slightly greasy residue
Easy, one-step application 
Waterproof 

5. Best for Extra-Large Dogs: Onguard Plus Flea & Tick Spot Treatment for Dogs, 89-132 lbs

Best for Extra-Large Dogs
Onguard Plus Flea & Tick Spot Treatment for Dogs, 89-132 lbs
  • Flea and tick spot treatment for dogs.
  • Kills all life stages of fleas and ticks on dogs.
  • Available in boxes containing three, six, or 12 monthly doses.
  • For dogs who are at least 8 weeks old and weigh between 89 and 132 pounds.
Check Chewy

The final option you have for Onguard flea and tick treatment is for extra-large pups. This is for dogs that weigh between 89 and 132 pounds. Customers rate it 3.8 out of five stars. One customer shared that she has a large furry dog that weighs well over 100 pounds. She just squeezes this product between her shoulder blades, and it pretty much stops the itching for a whole month. She’s convinced and will continue to buy it again and again. Another customer shared that she used a different brand for a couple of years and didn’t have any problems. She was hesitant to try a new product but she checked the ingredients and it matched up with what she was previously using. Except, this was not nearly as expensive. She tried it, and it works great, and now she uses it through all seasons.

Pros and Cons of Onguard Plus Flea & Tick Spot Treatment for Dogs, 89-132 Pounds

PROSCONS
Perfect dose for extra-large pupsThe consistency may be a little runny
Kills fleas and ticks 
Waterproof 

Criteria: What to Look for in Onguard Products

Animal Type

Onguard manufactures flea and tick treatments for both cats and dogs. You can’t use the cat one for dogs and you can’t use the dog one for cats. Make sure that you get the appropriate treatment for your pets.

Weight-Based Doses

The second consideration is that these doses are based on your pet’s weight. They’ve clearly identified on the packaging what weight range each of the doses is appropriate for. They’re pre-measured so giving a large dog’s dose to a small dog could have harmful side effects and giving a large dog a small dog’s dose can make it completely ineffective. Make sure to pay attention to those details before you make your final purchase.

Up Next, Explore More Products on Chewy…

About the Author

Angie Menjivar is a writer at A-Z-Animals primarily covering pets, wildlife, and the human spirit. She has 14 years of experience, holds a Bachelor's degree in psychology, and continues her studies into human behavior, working as a copywriter in the mental health space. She resides in North Carolina, where she's fallen in love with thunderstorms and uses them as an excuse to get extra cuddles from her three cats.

The 5 Best Onguard Products on Chewy Today FAQs (Frequently Asked Questions) 

What to do in your house if your pet has fleas?

If you notice that your pet has fleas, immediately wash your pet’s bedding, and your bedding if you allow your pet in your bedroom, and follow through with some heavy-duty vacuum cleaning. That means your floors, your upholstery, and any carpeted areas as well. Then, move forward with bathing your pat and applying flea and tick treatment.

What should I do if I see a tick on my pet?

If you see a tick on your pet, grab a pair of tweezers and grab the tick as close to your pet’s skin as possible. Pull it out in a slow and steady motion. Make sure that as you remove it, you keep the direction straight. If any pieces are left behind, it could lead to an infection. If you have any doubts, contact your veterinarian. Then, make sure that you follow through with some flea and tick treatment to prevent any further issues with ticks.

Can fleas jump from pets to humans?

Fleas can jump from pets to humans and from humans to pets. They can jump long distances but once they start producing eggs, they fall off and then they start looking for a new host. If you notice fleas on your pets, get some flea and tick treatment right away and thoroughly clean your home.

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